Therapeutics · Metabolic Health

Tirzepatide earns its first outcomes label

FDA approved tirzepatide to reduce MACE in adults with type 2 diabetes at cardiovascular risk. The claim rests on SURPASS-CVOT against dulaglutide, an active comparator, with an 8% relative reduction.

By longevitydocs™ editorsSep 6, 2026
Tirzepatide earns its first outcomes label
Therapeutics · Metabolic Health

The Lp(a) drug moved the number, not the outcome

Novartis and Ionis reported topline Phase III results from Lp(a)HORIZON on September 4: 8,323 patients with elevated Lp(a) and established cardiovascular disease on guideline-directed therapy.

By longevitydocs™ editorsSep 6, 2026
The Lp(a) drug moved the number, not the outcome
Therapeutics · Metabolic Health

Semaglutide, started late, extended life in mice

Female mice started daily semaglutide at 20 months, roughly a human mid-60s, and stayed on it for life. Median lifespan rose from 742 to 834 days, about 12%.

By longevitydocs™ editorsSep 6, 2026
Semaglutide, started late, extended life in mice
Therapeutics · Supplements & Peptides

Inside the longevitydocs Peptide Mastermind

If you walked into that room, you could feel it, the curiosity, the energy, the collective intelligence. From biology to regulation, the debate was intense, deeply respectful, and often humbling.

By David Luu, MDOct 7, 2025
Inside the longevitydocs Peptide Mastermind
Therapeutics · Supplements & Peptides

Peptides: meet the doctors speaking at the Mastermind

That’s why we’re bringing together the physicians who study, research, prescribe, and teach about peptides, so you can learn directly from the best how peptides can transform your practice, improve patient outcomes, and keep you at the forefront of modern medicine.

By David Luu, MDAug 10, 2025
Peptides: meet the doctors speaking at the Mastermind

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