A member asked for a recommended TRT course. Another answered that formal TRT certification courses are largely commercial products aimed at non-physician prescribers, and suggested starting with the AUA and Endocrine Society guidelines, the latter solid but conservative.
A third member proposed building a curriculum with an LLM such as Claude, using a detailed prompt covering the diagnostic workup, primary versus secondary hypogonadism, treatment options and dosing, monitoring, side effects, contraindications, fertility-preserving alternatives and informed consent, with instructions to cite guideline positions and flag controversy.
Two members added the caveat: LLMs drift back to standard society guidelines even when prompted otherwise, and longevity practice does not fit neatly inside conventional guidelines. Prescribers need both the guideline baseline and a clear way to document and explain off-label choices within medically supervised care.
Key takeaways
- Start with the AUA and Endocrine Society guidelines rather than a commercial certificate.
- An LLM can draft a structured physician-level curriculum, but treat it as a scaffold and review every line.
- Be ready to document and explain any decision outside the guidelines.
From Buzz in the chat, the longevitydocs™ Sunday newsletter, September 13, 2026. Member discussion, not clinical guidance.
Originally published in The Longevity Medicine Intelligence newsletter.
